Jul 8, 2006

Genetic Engineering Fuses Spider Silk and Silica

Bioengineers at Tufts University have created a new fusion protein that for the first time combines the toughness of spider silk with the intricate structure of silica. The resulting nanocomposite could be used in medical and industrial applications, such as growing bone tissue.
 
From the article:
 
Silica provides structural support to diatoms (single-celled organisms known for their remarkable nanostructural details) while silk proteins from spiders and silkworms are more flexible, stronger and able to self-assemble into readily defined structures. The Tufts researchers were able to design and clone genetic fusions of the encoding genes for these two proteins, and then generate these genetically engineered proteins into nanocomposites at ambient temperatures using only water. In contrast, high temperatures and harsh conditions are typically required by geochemical and industrial synthesis of silica in the laboratory.
 

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